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Calculation of structure motion and pore radius The closure and opening of the LBD bi-lobe was quantified by measuring the D2 lobes shift relative to its position in the apo structure

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This interaction amplifies the effectiveness of growth factors, supporting processes such as mitogenesis (cell division), motogenesis (cell movement), morphogenesis (structural development), neurogenesis (nervous tissue growth), stem cell production, and cellular protection against injury

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At the end of the experiment, mice were anesthetized with Avertin (300 mg/kg body weight) after 4 h of fasting