85 Moreover, the phagocytic activity of macrophages and monocytes significantly decreases during aging, leading to the accumulation of unphagocytosed debris, chronic sterile inflammation, and the exacerbation of tissue aging and damage
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10.1126/scitranlsmed.3000154 37
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Roberts DW, Lee WM, Hinson JA, Bai S, Swearingen CJ, Stravitz RT, Reuben A, Letzig L, Simpson PM, Rule J, Fontana RJ, Ganger D, Reddy KR, Liou I, Fix O, James LP
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