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"It's not a substitute for things we know are effective increasing cigarette prices by raising taxes, funding evidence-based tobacco cessation programs, and passing smoke-free laws." Nonsmoking advocates like McGoldrick call the combination of those efforts the winning trifecta

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[79] found if participants were to regularly use only e-cigarettes, their perceived risk of developing a heart attack next year was 34.6%, significantly lower than the perceived risk of regularly smoking only tobacco cigarettes (56.2%) and significantly higher than the perceived risk of no-nicotine use (15.2%)

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