Heffernan 2001a No hyperglycaemia observed in animal models even at doses producing significant fat oxidation
If the patient is suspected to be sensitive to cobalt or other components of cobalamin, an intradermal test dose is recommended.[12][15] Several laboratory tests should be performed prior to treatment with cyanocobalamin, including serum vitamin B12, folate, iron, hematocrit, and reticulocyte count
Repeated freeze-thaw cycles are not recommended because they may reduce material quality
Most patients tolerate the injections well
Consistent B12 supplementation can help reduce the risk of neurological issuesincluding memory loss, mood disturbances, and cognitive declineby supporting brain and nerve health
Goldstein, PhD (Thymosin Beta-4/TB-500 Primary Investigator) Department of Biochemistry and Molecular Medicine (Emeritus) George Washington University School of Medicine and Health Sciences, Washington, D.C