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Superior Sagittal Sinus, Portal and Caval Vein and Abdominal Aorta Pressure Recording Ligation of the superior sagittal sinus immediately overwhelms normal (negative) pressure, and induces the increased (positive) pressure, along with the severe portal and caval hypertension (portal hypertension exceeding caval hypertension), and aortal hypotension, persisting throughout the entire experimental period (Figure 5)

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The administration is carried out safely and comfortably by trusted medical professionals