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mTORC2 modulates the amplitude and duration of GFAT1 Ser-243 phosphorylation to maintain flux through the hexosamine pathway during starvation

MMAE, monomethylauristatin E

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This includes sleep optimization, stress reduction strategies, and appropriate treatment of anxiety or depression

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In the endoplasmic reticulum, it also acts like a built-in quality-control partner, supporting proper protein folding and helping prevent misfolded proteins from accumulating