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Prospective studies that repeatedly measure smoking behavior, pulmonary exposures, and immune-aging markers including after cessation could clarify whether immunosenescence mediates the harmful effects of smoking and whether these processes can be slowed or reversed
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The Associations 2020 scientific statement Medical Marijuana, Recreational Cannabis, and Cardiovascular Health, notes that while marijuana, also known as cannabis, may be helpful for some other medical conditions, it does not appear to have any well-documented benefits for the prevention or treatment of cardiovascular diseases (CVD)