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and glutamine consumption promotes endometrial tumor cell death, inhibiting autophagy (a stress response mechanism in this context), after estrogen incubation and c-myc activation [173]

Finally, prospects for ferroptosis-based interventions and future directions point to several promising treatment avenues, including regulating iron homeostasis via chelators or TfR1/FPN modulation, using antioxidants and lipid peroxidation inhibitors to target GPX4 and ACSL4, or employing gene therapies and stem cell/exosome approaches to combat ferroptosis

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Individuals with autism not only demonstrate decreased glutathione levels but also show deficiencies in other transsulfuration metabolites such as taurine, sulfate, and cysteine

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