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The secondary outcomes to be measured include the safety of both administration routes, quality of life (measured using the EuroQoL-5D questionnaire) and adherence to treatment

Its used for pernicious anemia, malabsorption syndromes, and certain neurological disorders linked to B12 deficiency

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"Some of the side effects we found, like nausea, are well known, and that shows that the method is picking up a real signal," says Sharath Chandra Guntuku, Research Associate Professor in Computer and Information Science (CIS) at Penn Engineering and the study's senior author

B12 does not provide any extra energy if you are not deficient