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Madonna R, Giovannelli G, Confalone P, Renna FV, Geng Y-J, De Caterina R

In milder or borderline cases, high-dose oral vitamin B12 may be sufficient, depending on absorption and clinical context

Longitudinal effects of dimethyl fumarate on patient-reported outcome measures in multiple sclerosis: treatment satisfaction, quality of life, depressive symptoms, sleep, and work productivity

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doi: 10.1002/ptr.5274 237

Together, these changes maintain a persistent, systemic, and low-grade inflammatory response