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The resulting energy deficit manifests clinically as debilitating fatigue and post-exertional malaise (PEM), hallmark symptoms of both Long COVID and ME/CFS

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B12 injections deliver a direct dose of vitamin B12 into your muscle

During an IV therapy push, your provider uses a syringe to directly inject various nutrients through your IV line

Reporting summary Further information on research design is available in the Nature Research Reporting Summary linked to this article

In severe cases that do not respond to first-line approaches, external therapies that modulate nerve function and more invasive treatments such as medications, deep brain stimulation, and cochlear implants may be considered