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Renal Function and Dialysis Research Kidney disease profoundly affects L-Carnitine homeostasis, creating a research area at the intersection of renal physiology and metabolism: Renal Carnitine Handling: Investigation of tubular reabsorption via OCTN2, urinary excretion patterns, and renal threshold determinations

The clinical relevance of these changes was further supported by the reduction in mean OFF time, which correlated with a reduction in ON time with troublesome dyskinesia

Pflugers Archiv Eur J Physiol (2004) 449(2):13242

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