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Actual Size RSC Adv ., 2021,11, 38161-38171 Can Med Assoc J

117 LacabanneD.FogeronM.-L.WiegandT.CadalbertR.MeierB

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Thompson, S

Intestinal permeability, low microbial diversity, gut infections, and chronic digestive inflammation can all maximize the activation of the immune system

These include diet, lack of sleep, stress, genetics, and especially exposure to the damaging rays of sunlight that have been reviewed in detail elsewhere and will be presented, in brief, below [10, 14, 16]