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Results showed dose-dependent weight loss reaching 22.5% at the highest dose over 72 weeks

The study included both in vivo analysis from two phase 2 clinical trials and in vitro experiments using primary human hepatocytes

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Administered as a once-weekly subcutaneous injection, tirzepatide is available in doses ranging from 2.5 mg to 15 mg, with recommended dose escalation in 2.5 mg increments approximately every 4 weeks to minimize gastrointestinal side effects

Before each use, the rubber septum should be swabbed with 70% isopropyl alcohol and allowed to air dry completely