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Retrieved August 13, 2009

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After performing an adjusted logistic regression analysis, dual smoking was found to represent a significant contributor to alcohol dependence, whereas never smokers were significantly less likely to be alcohol dependent

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Compared with traditional meta-analysis using linear mixed effect models, MR-BRT relaxes the assumption of a log(linear) relationship between exposure and risk, incorporates between-study heterogeneity into the uncertainty of risk estimates, handles estimates reported across different exposure categories, automatically identifies and trims outliers, and systematically tests and adjusts for bias due to study designs and characteristics