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Furthermore, our data reinforce the compartmentalized nature of Fe-S cluster synthesis itself, as analysis of extramitochondrial Fe-S protein stability indicated varied sensitivity towards cysteine limitation that was not seen with mitochondrial proteins

Using sensitive testing methods like mass spectrometry, traces can be detected in urine for up to 4 days

At least two categories of non-histone substrates are deacetylated by HDACs, including transcription factors and non-transcription factors

Discontinuation due to adverse events was about 4% across all dose groups