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[DOI] [PMC free article] [PubMed] [Google Scholar] 190.Whittle B.J., Boughton-Smith N.K., Moncada S

Platelet intrinsic apoptosis relies on the mitochondrial apoptosome-mediated caspase-9/caspase-3-dependent mechanism, is tightly regulated by Bcl-XL, Bak, and Bax, and lacks the Fas receptor present on erythrocytes [499]

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Because it targets the bacteria specifically, doxycycline doesn't harm human cells, which is why it's generally safe when used as directed