The stroke is invariably accompanied by the breach of the blood-brain barrier and infiltration of blood-borne elements into the brain parenchyma
the other is that excessive lipid peroxidation leads to the thinning and the increased curvature of the membrane, resulting in membrane instability and micelle formation, eventually causing ferroptotic cell death ( PUFAs in the phospholipids (PLs) of cell membranes, rather than mono-unsaturated FA, cholesterol, and cardiolipin, are highly prone to lipid peroxidation (Yang et al., 2016)
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The Fifth Circuit Showdown: OFA v
doi: 10.1038/s41380-021-01248-1 366 TmerZ.MllerL