doi: 10.1126/science.aad3369, 163 ZhongL.QinL.DingX.MaL.WangY.LiuM.et al
For example, acetate produced by Bifidobacterium longum inhibits the carcinogenic IL-6/JAK1/STAT3 signaling pathway by activating hepatocyte GPR43, thereby preventing the progression of NAFLD-related liver cancer (NAFLD-HCC)
Medical Radiology and Radiation Safety
Western blot analysis demonstrated that Formononetin significantly decreased the level of p-mTOR, p-pS6k, indicating that exposure to Formononetin could potentially impact the activity of the mTORC1 complex (Figures 3A, B)
Via the activation of TLR4/MAPK signaling in KCs ( In addition to HSCs, in an injured liver, hepatocytes and bile duct cells can also transform into fibroblasts via the process of epithelialmesenchymal transition (EMT), and excessive extracellular matrix (ECM) deposition by fibroblasts contributes to liver fibrosis
S., Gerrits, W