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Fearing, B

10.1371/journal.pone.0202102 [DOI] [PMC free article] [PubMed] [Google Scholar] Dwivedi, S

demonstrated that HSCs from autophagy-deficient C57BL/6 mice were unable to process cytoplasmic lipid droplets, reducing the availability of free fatty acids (218)

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Concentrations of the peptide up to 500 ng/mL failed to increase proliferation of mouse C2C12 cells or primary human skeletal muscle myoblasts, failed to inhibit myoblast differentiation, and failed to activate the signaling responses previously attributed to it, even as mature IGF-1 and full-length IGF-1Eb produced robust responses in the same assays