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However, LUT-EX@gel significantly lowered IOP within the first three hours (18% 3.3%), though this effect was not sustained over seven days as observed from the decrease in percent reduction of IOP (Fig

The sequence reads across all samples achieved a mean sgRNA count of at least 546, with less than 2.2% of sgRNAs showing complete depletion (Supplementary Data 2)

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If you do consider this approach, start with minimal doses of each and assess your response before increasing