Those red eyes are the result of vasodilation, caused by the effects of THC (delta-9 tetrahydrocannabinol) and other cannabinoid compounds on blood vessels in the eye
Tobacco companies claim that heat-not-burn products are less harmful than cigarettes because when tobacco burns, or combusts, it produces more than 7,000 chemicals that are found in cigarette smoke

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Extrapolating to the U.S
In lung cancer, TAMs are the most abundant immune cells present in the TME [184], and they were reported to promote the proliferation, epithelialmesenchymal transition and metastasis of cancer cells, which results in poor patient outcomes [185, 186]
In those days, it was considered crude to smoke this cigarette because the heavy smoke was irritating to the eyes and nose