In addition to direct damage to the ovaries, oxidative stress can also promote the development of other ovarian aging-related mechanisms, including telomere shortening, mitochondrial dysfunction, inflammation, and apoptosis
We hypothesized that there might be a transient lack of metabolically available antioxidants that could induce a suboptimal quality of ovulation and, eventually, of (or some) embryos
Ive done it
Harvard Dataverse , (2019)
High GSSG can actually promote pro-oxidative signaling, meaning you could be creating the very oxidative stress youre trying to combat
Cells were treated with 1 g/ml Doxycycline to induce the MLKL overexpression, and for all experiments, the cells between passage three and seven were used