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Indeed, the authors showed that the TNBC LAR subtype, characterized by high expression of the androgen receptor, an increased ROS accumulation, and FA synthesis making LAR tumors highly sensitive to ferroptosis [22]

Pharmaceutical Profiling in Drug Discovery for Lead Selection

In certain animal studies, its been found that IGF-1 may help protect against Parkinsons disease and induce clearance of brain amyloid-betas, which at high levels are associated with Alzheimers disease

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Weight changes depend on calorie intake, physical activity, hormonal balance, and metabolism, not on antioxidant supplements

However, limitations such as phytoconstituent leaching, instability, manufacturing challenges, high production costs, and commercialization hurdles need to be addressed by researchers in the future [101]