BPC-157 is one of the hottest compounds on the market right now with many people, especially in the bodybuilding and functional medicine space swearing by its beneficial effects for gut health and joint healing, among a whole host of other proposed possible benefits
However, all observed effects derive from animal models and in vitro research systems
Being a cytoprotection mediator native and stable in human gastric juice, suggests its easy applicability, including the per oral route, and strong distinction from the standard angiogenic growth factors, whose effects regularly need carrier addition [3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21,22,23,24,27,28,29,30,31,32,34,37,39,40]
It suppresses pro-inflammatory cytokines (e.g., IL-1, TNF-) and NF-B signaling, reducing inflammation linked to aging and injury
This creates theoretical concerns about cancer risk that require serious consideration
Translational Gap: Moderate to High