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Cullen, K.A., et al., Flavored tobacco product use among middle and high school studentsUnited States, 20142018

E-cigarettes have been proposed as an aid for smoking cessation but there is a need for more information on their efficacy and safety (Figure 3)

This premature skin damage associated with aging wrinkles delayed wound healing developing hidradenitis suppurativa developing psoriasis developing certain types of skin cancer Smoking Hair Theres also vasoconstriction DNA damage generation of free radicals hormonal effects Nails It may also affect your fingernails and toenails and increase the likelihood of fungal nail infections

Manufacturers must submit a Premarket Tobacco Product Application demonstrating that the product is appropriate for public health protection

Some patients notice numbness in the feet or cold hands