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Animal studies demonstrate that dihydrotestosterone (DHT) treatment upregulates ferroptosis-related markers ( e.g ., ACSL4) in ovarian cells, suggesting that androgens may exacerbate ferroptosis by modulating lipid metabolism genes ( 3.4 Epigenetic modifications Growing evidence has elucidated the critical role of epigenetic modifications in the pathogenesis and progression of PCOS

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J Am Chem Soc 137:1427514280

Anti-inflammatory functions of trimetazidine Preclinical studies Neutrophils are a key part of the immune system as the major type of white blood cells [147]

Durando M, Tiu H, Kim JS