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High attrition rates ultimately made it difficult to draw firm conclusions, and no significant difference in neuropathy severity emerged between treatment and placebo arms at the final analysis (Guo 2014)

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Add 2mL to a 10mg vial for 5mg/mL (5,000mcg/mL): 250mcg = 5 units, 500mcg = 10 units

VPAT is localized to neuronal synaptic vesicles, synaptic vesicle-like microvesicles in astrocytes, and mast cell secretory granules in the immune system (Hiasa et al., 2014