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The main pathological changes are found in the small airways with epithelial remodeling including goblet cell metaplasia, basal cell hyperplasia, leading to thickening of small airway walls and obliteration [4]

moreover, dry puff conditions should not always be cited as the sole factor promoting elevated levels of carbonyls

This paper reported that half of the inequalities in mortality between rich, educated men and poor, uneducated men can be accounted for by smoking deaths

DATE OF MANUFACTURE c.1950-1

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Easter M, Bollenbecker S, Barnes JW, Krick S