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Wnt/-catenin signaling plays a protective role in the Mdr2 knockout murine model of cholestaticliver disease

Body composition (lean/fat mass) and weight were longitudinally monitored via magnetic resonance imaging (MRI) at baseline, week 2, and week 4

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Syland E, Heier I, Rodriguez-Gallego C, et al

Younger animals typically exhibit higher levels of synaptic plasticity [21], more efficient neuronal signaling pathways [37], while aging, which is associated with declines in neurogenesis and reduced neural adaptive capacity, [22] which are related to impairments in cognitive function