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Moreover, d-carnitine increased the concentrations of fumaric acid, 2,3-methylenesuccinic acid, carbonic acid, AMP and phosphoric acid, which are by-products of the tricarboxylic acid cycle and oxidative phosphorylation

In addition, plain folic acid treatment supports only one of the three pathways for Hcy detoxification and may not work properly anytime the other pathways are concerned

Lippi G, Montagnana M, Salvagno GL, Guidi GC, Targher G (2008) Prevalence of folic acid and vitamin B 12 deficiencies in patients with thyroid disorders

Mislabelled or unapproved supplements not only endanger public health but can also lead to severe legal and reputational consequences for brands

doi: 10.1007/s13679-017-0262-y 136 MaratheCSPhamHWuTTrahairLGRigdaRSButtfieldMDMet al

Coenzyme Q10 and vitamin E deficiency in Friedreich's ataxia: predictor of efficacy of vitamin E and coenzyme Q10 therapy