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Specifically, significant improvement against the triggering of apoptotic mechanisms (involving apoptotic protease activating factor 1, Bax, and cytosolic cyto c proteins) with reduced acetylcholinesterase activity in the cerebellum was observed in the group treated with amla extract

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New England Journal of Medicine , 2025;393:648659

The present study hence focused on compounds, already in clinical use, with the potential to activate the Nrf2 stress response pathway

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Increased serum ALT activity, reflecting ongoing hepatic injury, is reported in 75% to 95% of dogs with chronic hepatitis.4, 7 Serum ALT activity may exceed 10 times the upper normal limit