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Its receptor selectivity profile also makes it applicable to comparative receptor pharmacology studies examining the structural determinants of erythropoietin receptor family member differentiation

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doi: 10.1038/s41523-020-00212-6 76 TuomistoAEMakinenMJVayrynenJP

Researchers gave 32 men with ED a combination of intranasal PT-141 (either 7.5 or 10 mg) plus oral sildenafil (50 or 100 mg), then used a RigiScan device to objectively measure erectile rigidity over 6 hours.Impressively, adding PT-141 to sildenafil increased the duration of erectile activity by over five-fold compared to sildenafil alone

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