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Thus, the activation of PI3K/Akt-1, NF-kB by growth factors, and TNF upregulated anti-apoptotic molecules Bcl-2, Bcl-xL, A1, and Mcl-1 maintain mitochondrial integrity by inhibiting the damage promoted by aggregation of the Pro-apoptotic (Bax, Bak, and Bid) factors (Fig

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(PubMed) Slattery ML, Potter JD, Samowitz W, Schaffer D, Leppert M

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Korean red ginseng extract prevents APAP-induced hepatotoxicity through metabolic enzyme regulation: The role of ginsenoside Rg3, a protopanaxadiol

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