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cassumunar extract) decreased bronchial hyperresponsiveness and significantly improved symptom scores in adult asthmatic patients with partially controlled symptoms with ICS, especially in patients with bronchial hyperresponsiveness and high FeNO levels at baseline ( Some in vitro studies have been performed using various immune cells, such as macrophages and lymphocytes, to evaluate the immunomodulatory effects of Z

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Importantly, P140 appears to selectively deplete hyper-activated autoreactive T and B cells while sparing normal immune cells