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If you experience any severe symptoms outside of minor swelling or bruising at the injection site, including significant pain at the injection site that has not gone away by the next day, call your doctor immediately.

7.1.1 Use of cytokine inhibitors Cytokines, particularly pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF- ), interleukin (IL)-1, and IL-6, are known to contribute significantly to BBB dysfunction and neuroinflammation following I/R injury (Jurcau and Simion, 2021)

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