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The real human data belong to different molecules/uses
However, Maiorino and co-workers recently redefined the catalytic motif of GPx1 as tetrad by establishing through mutagenesis study in Drosophila model that asparagine (Asn or N) residue was also essential for the catalytic activity of GPx1 [13]
Cumulative ROS can cause damage to biomolecules such as lipids, proteins and DNA, in addition to mitochondrial dysfunction [5]
Microdialysis with radiometric monitoring of L-[- 11 C]DOPA to assess dopaminergic metabolism: Effect of inhibitors of L-amino acid decarboxylase, monoamine oxidase, and catechol-O-methyltransferase on rat striatal dialysate
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