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This transporter, similar to yeast mitochondrial SAM carrier, was shown to be additionally localized in mitochondria, and to contains five transmembrane helices (Palmieri et al., 2006)

10.1146/annurev-biochem-060815-014922 Annu

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Additionally, studies reported diminished immunoreactivity of locus coeruleus processes and decreased CSF MHPG in suicidal bipolar subjects compared with controls (243, 244)