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The study is one of nine pieces of research on e-cigarettes to come out of the State and Community Tobacco Control Research (SCTC) Initiative, funded by the US National Cancer Institute at the National Institutes of Health, and published in the supplement

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PMI's clinical data scrutinised by the US FDA, who authorised IQOS in 2020 as a "modified risk tobacco product" shows reductions in many of the harmful chemicals associated with cigarette smoke

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