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The lack of MRS dACC changes in the Recent onset group in this or other studies does not amount to a decisive refutation of the glutamate neurotoxicity hypothesis because the relationship of static MRS glutamate to synaptic status is too uncertain and the time of onset of the putative glutamate excess relative to psychosis onset is unknown

This effectiveness must be correlated to the capacity to manage the molecular mechanisms underlying vascular function, metabolic equilibrium, and redox states through the intentional management of specific antioxidants (Sorriento et al., 2018)

Its structural stability allows it to remain intact in various experimental conditions

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Catalpol from Rehmannia glutinosa targets Nrf2/NF-B signaling pathway to improve renal anemia and fibrosis