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Acknowledgements This review was supported by the Department of Gynecology, Peoples Hospital of Peking University

Laboratory tests: Fasting Lipid profile was assessed after 10 h of fasting, and dyslipidemia was defined as the presence of any of the following four measurements: high total-cholesterol ( 200 mg/dL), high LDL-cholesterol ( 130 mg/dL), low HDL-cholesterol ( 35 mg/dL), or high triglycerides ( 130 mg/dL) 21

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Moreover, the persistent accumulation of inflammatory memory may lead to stem cell dysfunction, resulting in exaggerated immune responses and increased susceptibility to autoimmune diseases (e.g., psoriasis) and chronic inflammatory conditions

L-arginine supplementation in peripheral arterial disease: no benefit and possible harm

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