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The 30 mL estimate came from animal studies and is framed around intravenous dosing, so read it as a guardrail rather than a hard limit

Evid Based Complement Alternat Med (2022) 2022:8589121

While EECp failed to downsize bladder edema with the comparable efficiency of mesna, it enhanced significantly the histopathological scores and diminished myeloperoxidase activity in the lung, as well as, the levels of malondialdehyde in the bladder, lung, and spleen tissue

It also aids recovery from injuries that involve damaged blood vessels

In other words, we will not use the same cost report for both the FY 2019 and the FY 2018 time periods.) In general, we note that, for purposes of the Factor 3 methodology, references to a fiscal year cost report are to the cost report that spans the relevant Federal fiscal year period

Several adverse effects have been documented, ranging from mild to severe