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[DOI] [PubMed] [Google Scholar] 114.Shevchenko K.V., Nagaev I.Y., Andreeva L.A., Shevchenko V.P., Myasoedov N.F

and Mooney, D.J

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Dihexa acetate dropped off the FDA's Category 2 restricted list on April 22, 2026, as part of the agency's 12-peptide reclassification action

The findings cited above are taken from preclinical, animal-model, and in vitro studies and are reported here for research context only

Moreover, specialized pro-resolving mediators (SPMs), a class of PUFA-derived lipid mediators, regulate pro-inflammatory and resolution pathways, playing significant anti-inflammatory and neurological roles, which in turn may be beneficial in alleviating the symptomatology of migraine