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Macrophages and mast cells clear damaged tissue and cellular debris, while secreting proteins essential for wound contraction and overall tissue healing

batch-to-batch variation, contamination with pathogens or lead/arsenic, product- product variability users assume is uniform (but can be diverse within a supply chain), herb-drug interactions like modulating CYP enzymes that change the pharmacokinetics of drugs with narrow therapeutic windows all contribute to problems related to reproducibility and safety (195)

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