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For tirzepatide, this might mean escalating to 10-15 mg for active weight loss, then reducing to 5-7.5 mg for maintenance

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Since an interaction between the host and phage had already been identified in the earlier AG screen, infections were not restriction to a single phage replication cycle, but allowed to proceed further to achieve full depletion of the phage-sensitive Tn5-knockout mutants in the pool