In horses, it can improve the clinical signs in cases of a tying-up syndrome which is painful and manifests with lack of mobility
In one mouse study, researchers found that the peptide reduced the pain felt by the animals in their paws when placed on a mildly hot plate. The authors explained that this could be because GHK is similar in structure to cimetidine, a histamine H2 receptor antagonist sometimes given to reduce pain in certain digestive conditions.3 10 In rodents, doses as low as 0.5mg/kg were found to be effective in delivering these anti-pain effects.25 In a 70kg human, an equivalent dose would be around 5.6mg, though thats likely higher than necessary: pharmaceutical-grade GHK-Cu normally ranges from 0.5 mg to 2.5mg per injection
Peptides can support fat loss and help preserve muscle when paired with resistance training and smart nutrition
B12 is as important to patients as insulin is to diabetics
Therefore, it isnt uncommon to see tesamorelin given as an off-label prescription for weight loss or muscle growth
One of the two patients who had therapy reported experiencing constipation (18)
