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Thus, the unregulated access and non-compliant use of APAP leading to an overdose is one of the leading causes of drug induced liver injury ( APAP is a commonly used fever reducer in pediatric populations

Rats were then divided into three groups with 12 animals each

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In a preferred embodiment, the process of the invention uses special equipment for crystallisation, as it has been observed that particular stirrers with low shear strength give rise to rapid, complete dissolution of the product in amorphous form and better reproducibility of precipitation, especially when the alpha crystalline form is to be obtained