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The selected reaction monitoring (SRM) mode was used for detection and external quantification, using the following transitions in the positive ion mode: m/z 434.2 to m/z 321.2 (Venetoclax, qualifier), m/z 868.3 to m/z 321.2 (Venetoclax, quantifier), m/z 945.3 to m/z 404.2 (AZD-4320), m/z 150.1 to m/z 133.1 (methionine), m/z 148.1 to m/z 84.1 (glutamic acid) and m/z 120.1 to m/z 74.1 (threonine)

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This problem has yet to be solved, although for Dyt1 at least there is some indication that the genetic pathway in the cerebellum is at fault [65]

doi: 10.3390/antiox9090901

A secondary route is the microsomal ethanol oxidation system (MEOS)

doi:10.3389/fneur.2023.1239182 31