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The S100B/RAGE axis in Alzheimers disease

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Peptides function as signaling molecules that influence cellular processes, which distinguishes them from steroids (lipid-based hormones derived from cholesterol) and SARMs (selective androgen receptor modulators that target androgen receptors)

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Their antioxidative properties stem from neutralizing ROS via direct radical scavenging or by enhancing endogenous antioxidant defense mechanisms, such as the Nrf2 pathway, reducing oxidative cellular damage 189