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Mechanistic role of autophagy signaling in epilepsy mTOR pathway Of note, mTOR is a serine-threonine kinase that forms two protein complexes termed mTORC1 and mTORC2 (Wong 2013)
PEGylated PLGA nanoparticles as a smart carrier to increase the cellular uptake of a coumarin-based monoamine oxidase B inhibitor
Arthritis Research & Therapy
To our knowledge and at the time of this review, this has been the only study to date evaluating renal effects of hyperoxia-induced IL-6 and Smad2 signaling, and there has been no further proposal for pharmaceutical interventions to modulate this pathway for renal protection during high oxygen supplementation
Moreover, it has the potential to improve the lipid metabolism and promote weight reduction in obese patients, besides to alleviate CNS-related diseases (Schizophrenia and MS) symptoms
